Surveillance of severe influenza-associated encephalopathy and related complications in US children SS-75D301-2026
Summary
AI-generated · Jan 17, 2026Surveillance of severe influenza-associated encephalopathy (IAE) in hospitalized children up to 18 years old with laboratory-confirmed influenza, using standardized case definitions. Collect detailed clinical information on identified IAE cases to identify risk factors for severe disease, describe the disease course and spectrum of presentations, and assess the impact of clinical interventions, including influenza vaccination and antiviral medications.
Also assess patients’ vaccination status and other hospitalization details by performing medical record reviews and accessing statewide vaccine registry data. See the draft Performance Work Statement for full task details.
The specific goals of this project are to: Perform surveillance for severe IAE in hospitalized children with laboratory-confirmed influenza (age ?18 years) using standardized case definitions. Collect detailed clinical information on identified IAE cases to assess risk factors for severe disease, describe the disease course and spectrum of disease, and assess the impact of different clinical interventions including influenza vaccination and antiviral medications. Assess influenza vaccination status of patients and other information about the hospital course by conducting medical record reviews and statewide vaccine registry reviews. SEE THE DRAFT PERFORMANCE WORK STATEMENT
From Sources Sought posted on Jan 16, 2026Notice history
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Place of Performance
USA