Recovery and Re-Energization of Bruker 14T MRI Magnet NINDS03350

The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The Mouse Imaging Facility (MIF) was established in 1999 as a shared resource dedicated to providing access to modern radiological imaging methods optimized for studying mice (and other animals) and developing state-of-the-art anatomical, functional and molecular imaging techniques for the entire intramural NIH community. Currently, the MIF imaging resources include magnetic resonance imagers (MRI), microcomputed tomography (Micro CT), optical imaging including bioluminescence and f luorescence, high f requency ultrasound with photoacoustics imaging, other animal physiologic monitoring equipment. The MIF has considerable technical expertise in animal imaging. The MIF mission requires that all imaging equipment be in optimum working order for maximum use by NIH researchers. The 14T magnet was used for imaging nearly 24 hours per day, 7 days per week, so its quench has had a signif icant impairment to ongoing studies that were started before January 20, 2025. It is imperative to restore the 14T magnet for imaging for studies that are currently delayed. The objective is to bring the magnet back online for use as quickly as possible. Failure to procure these services will result in continued disruption of ongoing research, possible loss of NIH investment in research resources currently involved in the ongoing studies, and an inability to complete ongoing imaging studies that began before January 20, 2025. This request falls under the category of instrument maintenance and service and ongoing research experiments. Order relates to ongoing research experiments that began before January 20, 2025, including new experiments related to studies that began prior to January 20, 2025.