Protein Biologic Analyzer 1333ND25QNB640234

FBO ANNOUNCEMENT: PRESOLICITATION NOTICE, NOTICE OF INTENT ACTION CODE: SPECIAL NOTICE CLASSIFICATION CODE: 66 – Instruments and Laboratory Equipment SUBJECT: Protein Biologic Analyzer SOLICITATION NUMBER: 1333ND25QNB640234 DESCRIPTION: The National Institute of Standards & Technology (NIST) intends to negotiate on a brand name basis under the authority of FAR 13.105, for a Solentim ICON Analyzer. Brand Name Justification is based on the following: The Biomolecular Structure & Function (BSF) Group in the Biomolecular Measurement Division of the Materials Measurement Laboratory within NIST, is establishing a biomanufacturing testbed for representative processes used during the production of therapeutic proteins. A Protein Biologic Analyzer integrates all capabilities to perform at-line rapid measurements of mammalian cell culture to include clonal screening, colony outgrowth & protein biologics titer and glycan characterization supplemented by automated data monitoring, acquisition, and reporting for per cell protein expression and glycan distribution.

COMBINED SYNOPSIS/SOLICITATION 1333ND25QNB640234 Protein Biologic Analyzer This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6- Streamlined Procedures for Evaluation and Solicitation for Commercial Items, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation document will not be issued. This solicitation is being issued under the authority of FAR Part 13 Simplified Acquisition Procedures. This solicitation is a Request for Quotations (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2025-05, effective 8/7/2025. The associated North American Industrial Classification System (NAICS) code for this procurement is 334516 Analytical Laboratory Instrument Manufacturing with a small business size standard of 1,000 employees. The acquisition is a Brand-Name Only Full and Open competition. The National Institute of Standards & Technology (NIST) Material Measurement Laboratory (MML), Biomolecular Structure & Function (BSF) Group (1) advances novel measurement methods and models for the determination and analysis of the structure and function of biological macromolecules, including lipids, DNA, RNA, and proteins and macromolecular complexes and assemblies formed by these molecules; (2) advances methods to determine the physical and chemical factors which determine the specific interactions of macromolecules with cofactors and ligands; (3) studies the relationships between biomolecule structure, dynamics, function, and energetics using computational, biophysical and biochemical techniques; (4) develops reference databases for these properties; and (5) advances measurement methods for engineering complex biological systems. The Group is establishing a bio-manufacturing testbed for representative processes used during the production of therapeutic proteins. To support this work, the group requires capabilities to perform at-line rapid measurements of mammalian cell culture clonal screening, colony outgrowth and protein biologics titer and glycan measurements. This is a Brand Name Only procurement: Solentim ICON