Evaluating the utility of bulk RNA transcriptomics FDA-CDER-25-128751
Summary
AI-generated · Aug 24, 2025Provide bulk RNA sequencing/transcriptomics service to profile both coding and noncoding RNA expression in primary human hepatocytes, comparing treated versus untreated cells to identify transcriptional changes caused by the treatment. The work centers on generating bulk transcriptomics data from treated PHHs to quantify RNA expression changes and understand the treatment's impact.
Three notices contain identical requirements; no additional terms, changes, or new information are indicated.
The objective of this contract is to obtain service required to complete bulk transcriptomics of RNAs from treated and untreated primary liver hepatocytes. Transcriptomics data generated from bulk RNA sequencing will identify changes occurring for both coding and noncoding RNAs in primary human hepatocytes (PHHs) following treatment. Obtain the service required to complete bulk RNA sequencing or transcriptomics from treated primary liver hepatocytes (PHHS). Transcriptomics data generated from bulk RNA sequencing will quantify expression of both coding and noncoding RNAs in PHHs.
From Combined Synopsis/Solicitation posted on Jul 02, 2025The objective of this contract is to obtain service required to complete bulk transcriptomics of RNAs from treated and untreated primary liver hepatocytes. Transcriptomics data generated from bulk RNA sequencing will identify changes occurring for both coding and noncoding RNAs in primary human hepatocytes (PHHs) following treatment. Obtain the service required to complete bulk RNA sequencing or transcriptomics from treated primary liver hepatocytes (PHHS). Transcriptomics data generated from bulk RNA sequencing will quantify expression of both coding and noncoding RNAs in PHHs.
From Combined Synopsis/Solicitation posted on Jul 07, 2025The objective of this contract is to obtain service required to complete bulk transcriptomics of RNAs from treated and untreated primary liver hepatocytes. Transcriptomics data generated from bulk RNA sequencing will identify changes occurring for both coding and noncoding RNAs in primary human hepatocytes (PHHs) following treatment. Obtain the service required to complete bulk RNA sequencing or transcriptomics from treated primary liver hepatocytes (PHHS). Transcriptomics data generated from bulk RNA sequencing will quantify expression of both coding and noncoding RNAs in PHHs.
From Combined Synopsis/Solicitation posted on Jul 10, 2025Notice history
3-
Combined Synopsis/Solicitation Posted Jul 02, 2025
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Combined Synopsis/Solicitation Posted Jul 07, 2025No changes from previous notice
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Combined Synopsis/Solicitation LATEST Posted Jul 10, 2025No changes from previous notice
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USA