AN42--Metabolomics and Proteomic Lab Services at Durham VAMC 36C24625Q0842
Summary
AI-generated · Aug 23, 2025Duke University Substrate Services Core & Research Support at the Durham VA Medical Center will perform metabolomics and proteomic lab services as part of a Research and Development study. The contractor will prepare liver tissue and conduct targeted LC-MS/MS to profile metabolites using Q500, oxylipin, and bile acid kits, and will profile proteins in tissue. This enables targeted quantification of amino acids, biogenic amines, acylcarnitine, hexoses, lipids, phospholipids, bile acids, fatty acids, and proteins to inform a plasma-based signature of outcomes after HCV cure and analyses relevant to Veterans with severe liver disease.
Period of performance is a one-time service. The procurement is justified as sole-source under FAR 13.106-1(b). This is not a competitive solicitation; no solicitation documents are available and telephone requests will not be accepted. If other firms have relevant past experience, they may submit a written notice with supporting evidence; responses will be considered, though the Government may, at its discretion, decide not to compete. Inquiries should be directed to the designated VA contact.
The Department of Veterans Affairs, Network Contracting Office (NCO) 6 intends to award a sole source purchase order to Duke University Substrate Services Core & Research Support at the Durham VA Medical Center in Durham, NC as part of a Research and Development study for the metabolomics and proteomic lab services that will inform our plasma-based signature of outcomes after HCV cure and are relevant to Veterans with severe liver disease analyses. The Contractor, Duke University, will prepare liver tissue and conduct targeted mass spectrometry (LC-MS/MS) to profile metabolites using Q500, oxylipin, and bile acid kits, as well as profile proteins in tissue. This allows for the targeted quantification of amino acids, biogenic amines, acylcarnitine, total hexoses, lipids, phospholipids, bile acids, fatty acids and proteins. Period of performance will be one-time service. Justification for this sole source procurement is in accordance with FAR 13.106-1(b) soliciting from a single source. This notice of intent is not a request for competitive quotes. No solicitation documents are available and telephone requests will not be accepted. However, any business that believes it can meet these requirements and possesses relevant past-experience and expertise may give written notice. Supporting evidence must be furnished in sufficient detail to demonstrate the ability to comply with the above requirement. Responses will be considered by the Government however, a determination by the Government not to compete the proposed acquisition based upon responses of this notice is solely within the discretion of the Government. NAICS Code 541715. Responses received by 10:00 am EST on Jun 27th, 2025, will be considered by the Government. Inquiries shall be emailed to Christian.rosadoramirez@va.gov. No telephone requests will be accepted.
From Special Notice posted on Jun 25, 2025Notice history
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